A lonely Australian girl (Toni Collette) and an elderly Jewish man (Philip Seymour Hoffman) in New York develop an unlikely friendship through letters.
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Movie theaters showing Mary and Max near Acapulco, Mexico:
| Toni Collette | Voice of Mary Daisy Dinkle |
| Philip Seymour Hoffman | Voice of Max Jerry Horovitz |
| Eric Bana | Voice of Damien |
| Barry Humphries | Voice of Narrator |
| Bethany Whitmore | Voice of Young Mary |