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This music hall and restaurant founded was in 1992 by Hard Rock Cafe founder Isaac Tigrett and his friend and investor Dan Aykroyd. It is a venue for live music and southern-inspired cuisine, whose clubs generate considerable income from world cultures, specifically blues music and folk art, and present a business model trademarked as "inspiration of music for the soul".
| 11/22 | 11:00a | House of Blues Gospel Brunch |
| 1:00p | House of Blues Gospel Brunch | |
| 8:00p | Train | |
| 11/25 | 7:30p | Raphael Saadiq |
| 11/27 | 8:00p | Randy Rogers |
| 10:00p | La Diabla | |
| 11/28 | 8:30p | Misfitsfeaturing Hell City Kings, Molotov Compromise & The Ghost Storys |
| 8:30p | Misfits | |
| 11/29 | 11:00a | House of Blues Gospel Brunch |
| 1:00p | House of Blues Gospel Brunch | |
| 11/30 | 6:00p | Taking Back Sunday |
| 7:00p | Concert By Anberlin | |
| 12/1 | 7:00p | Cafe Tacuba |
| 8:00p | Café Tacuba 20th Anniversary Tour | |
| 12/2 | 8:00p | Adam Richman of the Travel Channel's Man vs Food |
| 12/4 | 8:00p | Christmas with Aaron Neville and his Quintet featuring Charles Neveille |
| 10:00p | La Diabla | |
| 12/6 | 1:00p | Gospel Brunch |
| 12/7 | 7:30p | Trivium with Dirge Within |
| 8:00p | Into the Mouth of Hell We Tour |
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