What's In Your Blood? Molecular Deconvolution Of The Human Serum Antibody Repertoire In Health And Disease
We have developed a suite of proteomic, microfluidic, protein engineering and informatics technologies that has enabled the deconvolution of the identities and relative amounts of antibodies in biological fluids and the delineation of the relationships between antibody production and the relevant B cell immunological mechanisms. We have used this approach to elucidate a number of key questions in medicine and human health including: (i) what is the repertoire and functionality of antibodies elicited… Show more
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