De Novo Design Of Monomeric Proteins, Protein-Peptide Complexes And Multimeric Peptides
ABSTRACT: Proteins serve as vital components in our cellular makeup and perform many biological functions that are essential for sustaining life. An important feature which determines the functionality of a protein is the form of its three-dimensional structure. Elucidated protein structures can also serve as templates for de novo protein design which is of major importance in structure-based drug design and plays a pivotal role in the scientific challenge/roadmap: sequence to structure to function.… Show more
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